The Ohio River is the largest tributary of the Mississippi River, at nearly 1,000 miles from its headwaters in Pittsburgh, Pennsylvania to its mouth on the Mississippi River at Cairo, Illinois. The Ohio flows through or along the border of six states including Pennsylvania, Ohio, West Virginia, Kentucky, Indiana and Illinois.
| Month | Number of Cruises | From Price |
|---|---|---|
| Jul 2026 | 3 cruises | $5,275 |
| Sep 2026 | 1 cruises | Call For Price |
| Jun 2027 | 4 cruises | $6,299 |
| Jul 2027 | 5 cruises | $5,815 |
| Aug 2027 | 4 cruises | $5,815 |
| Oct 2027 | 1 cruises | $12,998 |
| Nov 2027 | 3 cruises | $5,999 |
| Jul 2028 | 2 cruises | $5,815 |
| Aug 2028 | 6 cruises | $5,815 |
| Sep 2028 | 6 cruises | $6,215 |
| Jul 2029 | 2 cruises | $5,815 |
| Aug 2029 | 4 cruises | $5,815 |
| Sep 2029 | 4 cruises | $6,215 |
| 14 Night Bayous Blues and Bluegrass Cruise from Louisville | Duration | Priced from |
|---|---|---|
Viking Mississippi 2 Sail Dates: 6/1/27; 6/15/27; 10/26/27; 11/9/27; See More Starting Port: Louisville, Kentucky, United States Ports of Call: Louisville, Owensboro, Henderson, Paducah, Cruising the Mississippi River, Memphis, Greenville... |
14 Nights |
$11,498per person
(double occupancy) |
| 14 Night Bayous Blues and Bluegrass Cruise from Louisville | Duration | Priced from |
|---|---|---|
|
Viking Mississippi 2 Sail Dates: 6/1/27; 6/15/27; 10/26/27; 11/9/27; See More Starting Port: Louisville, Kentucky, United States Ports of Call: Louisville, Owensboro, Henderson, Paducah, Cruising the Mississippi River, Memphis, Greenville... |
14 Nights |
$11,498per person
(double occupancy) |
| 7 Night Mississippi and Ohio River Explorer Cruise from Louisville | Duration | Priced from |
|---|---|---|
|
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7 Nights |
$5,999per person
(double occupancy) |
| 7 Night Mississippi and Ohio River Explorer Cruise from Louisville | Duration | Priced from |
|---|---|---|
|
|
7 Nights |
$5,999per person
(double occupancy) |
| 8 Night Ohio River Cruise and Land Tour from Pittsburgh | Duration | Priced from |
|---|---|---|
American Symphony 13 Sail Dates: 7/18/27; 7/26/27; 8/3/27; 8/11/27; 8/19/27; 7/16/28; 7/24/28; 8/1/28; 8/9/28; 8/17/28; See More Starting Port: Pittsburgh, Pennsylvania, United States Ports of Call: Pittsburgh, Wheeling, Marietta, Cruising the Ohio River, Cincinnati, Madison, Louisville |
8 Nights |
$5,815per person
(double occupancy) |
| 8 Night Ohio River Cruise and Land Tour from Pittsburgh | Duration | Priced from |
|---|---|---|
|
American Symphony 10 Sail Dates: 7/18/27; 7/26/27; 8/3/27; 8/11/27; 8/19/27; 7/16/28; 7/24/28; 8/1/28; 8/9/28; 8/17/28; See More Starting Port: Pittsburgh, Pennsylvania, United States Ports of Call: Pittsburgh, Wheeling, Marietta, Cruising the Ohio River, Cincinnati, Madison, Louisville |
8 Nights |
$5,815per person
(double occupancy) |
| 15 Night Grand Ohio River Cruise and Land Tour from Pittsburgh | Duration | Priced from |
|---|---|---|
|
American Symphony 3 Sail Dates: 8/27/27; 9/26/28; 9/27/29; See More Starting Port: Pittsburgh, Pennsylvania, United States Ports of Call: Pittsburgh, Cruising the Ohio River, Marietta, River Cruising, Maysville, Cincinnati, Madison... |
15 Nights |
$9,240per person
(double occupancy) |
| 15 Night Grand Ohio River Cruise and Land Tour from Pittsburgh | Duration | Priced from |
|---|---|---|
American Melody 3 Sail Dates: 7/31; 7/2/27; 7/16/27; 8/12/28; 9/11/28; See More Starting Port: Pittsburgh, Pennsylvania, United States Ports of Call: Pittsburgh, Cruising the Ohio River, Marietta, River Cruising, Maysville, Cincinnati, Madison... |
15 Nights |
$9,240per person
(double occupancy) |
| 8 Night Ohio River Cruise and Land Tour from Louisville | Duration | Priced from |
|---|---|---|
|
8 Nights |
$4,610per person
(double occupancy) |
| 8 Night Ohio River Cruise and Land Tour from Louisville | Duration | Priced from |
|---|---|---|
|
American Melody 3 Sail Dates: 7/10; 7/24; 8/26/28; 9/2/28; See More Starting Port: Louisville, Kentucky, United States Ports of Call: Louisville, Cruising the Ohio River, Madison, Cincinnati, Cruising the Ohio River, Marietta... |
8 Nights |
$5,275per person
(double occupancy) |
| 15 Night Grand Ohio River Cruise and Land Tour from Pittsburgh | Duration | Priced from |
|---|---|---|
|
American Melody 2 Sail Dates: 7/31; 7/2/27; 7/16/27; 8/12/28; 9/11/28; See More Starting Port: Pittsburgh, Pennsylvania, United States Ports of Call: Pittsburgh, Cruising the Ohio River, Marietta, River Cruising, Maysville, Cincinnati, Madison... |
15 Nights |
$9,240per person
(double occupancy) |
