American Melody
Category SSF - Seven Seas Suite Forward
Seven Seas Suite (Forward)
Photos are examples only. Actual cabin colors and features may vary.
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8 Night Upper Mississippi River Cruise and Land Tour from St Louis

Ship: American Melody
Cruise Line: American Cruise Lines
Sailed: Friday, Aug 28, 2026 from St Louis, United States
Ended: Saturday, Sep 5, 2026
The itinerary information below reflects the original day-by-day port of call schedule for the Friday, Aug 28, 2026 departure of the American Melody. If American Cruise Lines modified this itinerary for weather or operational reasons after departing , the modified schedule would not be reflected here.
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Day by Day Summary and Map

Day 1 - Friday - Aug 28, 2026
St Louis, United States
St Louis, United States
Enjoy a relaxing hotel stay and explore the city at your leisure before embarking on your cruise. Take in the striking skyline as it unfolds along the river, crowned by the iconic Gateway Arch, a defining landmark of one of the Midwest's most celebrated cities, where the Mississippi and Missouri rivers converge. Visit Gateway Arch National Park, where the Arch stands as a symbol of the nation's westward expansion. Discover downtown St. Louis, taking in the riverfront, Citygarden, Soulard, Lafayette Square, and Forest Park, or visit the renowned Anheuser-Busch (Budweiser) brewery to see the legendary Clydesdales.
Day 2 - Saturday - Aug 29, 2026
St Louis, United States
St Louis, United States
Cruise Begins
St Louis, United States
Board the ship and begin your travels along the Mississippi River toward Hannibal. From the sun deck, take in small towns and agricultural stretches that reflect the working landscape of this region. Take time to get comfortable in your stateroom and admire the scenery from your private balcony. Or participate in onboard enrichment activities that highlight the culture and history of the river. Don't miss cocktail hour, a chance to meet fellow travelers, before enjoying dinner inspired by local flavors.
Day 3 - Sunday - Aug 30, 2026
Hannibal, United States
Step into the world of Mark Twain in this idyllic river town, where the author's stories of Tom Sawyer and Huckleberry Finn come to life. Visit the Mark Twain Boyhood Home & Museum to experience life in the 1840s and the events that shaped his legendary writing. Stroll the preserved 19th-century streets and join a guided walk with a local interpreter, who brings the town's story to life through Mark Twain's own words. Visit Rockcliffe Mansion for stunning views of the Mississippi River, and explore Mark Twain Cave, one of the region's most famous natural attractions, for an unforgettable underground adventure.
Day 4 - Monday - Aug 31, 2026
Cruising the Mississippi River, United States
Settle into one of the spacious lounges aboard the riverboat as we continue cruising from Hannibal to Muscatine. On this stretch of scenic river cruising, the channel becomes narrower and we pass through additional locks while Mississippi River hillsides and dense forests rise along the shoreline. From the sun deck or your private balcony, relax and take in the view as we cruise through quieter stretches of the Mississippi River, with occasional sightings of regional wildlife.
Day 5 - Tuesday - Sep 1, 2026
Muscatine, United States
Along the upper Mississippi River in Iowa, Muscatine is a quiet river town with a relaxed pace and easy riverfront access, a noticeable change from the busier lower river cities. Walk the riverfront where hillside views and tree-lined shores create a serene backdrop for exploration. Step inside the National Pearl Button Museum to explore Muscatine's distinctive legacy as the "Pearl Button Capital of the World". Uncover the fascinating process of crafting buttons from freshwater mussels and see how this once-booming industry shaped the city's economy and riverfront identity. Then, venture to Pine Creek Grist Mill, a beautifully restored 19th-century landmark nestled within Wildcat Den State Park. As one of the oldest and most well-preserved gristmills between the Mississippi River and the Rockies, it offers a vivid glimpse into the region's early milling heritage and rural craftsmanship.
Day 6 - Wednesday - Sep 2, 2026
Dubuque, United States
Dubuque, Iowa, overlooks the Mississippi River and blends historic architecture with walkable streets. Stroll the revitalized riverwalk and wander the city's quaint avenues, where preserved buildings bring Dubuque's past to life. Ride the Fenelon Place Elevator for a unique view of the steep terrain. Immerse yourself in the National Mississippi River Museum & Aquarium with hands-on exhibits, live wildlife displays, and interactive lessons on river navigation. Travel to the iconic Field of Dreams Movie Site to experience cinematic history or observe local wildlife and plant life along the scenic waterway.
Day 7 - Thursday - Sep 3, 2026
Winona, United States
Winona is a scenic retreat, with an inviting downtown and peaceful riverfront trails that encourage discovery at every turn. Dive into the city's rich heritage at the Winona County History Center, where thoughtfully curated exhibits trace the stories and traditions of the community through time. Make your way to Garvin Heights Lookout, where panoramic views reveal the meeting of river, town, and surrounding farmland in one unforgettable scene. Art enthusiasts will appreciate the Minnesota Marine Art Museum, home to an impressive collection of European and American marine and fine art. Enhance your visit with a narrated boat excursion along the Mississippi River, offering insight into Winona's deep connection to this legendary waterway. Don't forget your camera and binoculars-this stretch of river is rich with wildlife, from soaring eagles to deer and turtles near the shoreline.
Day 8 - Friday - Sep 4, 2026
Red Wing, United States
Overlooking the northern riverbanks, Red Wing has inspired artisans for over 150 years, its striking cliffs and sweeping river views fueling generations of artistic creativity. Visit the Red Wing Pottery Museum to admire beautifully preserved stoneware and regional folk art that reflect the town's rich craftsmanship. Take in a performance at the Sheldon Theatre, one of Minnesota's oldest venues, known for featuring international artists and local productions. At the National Eagle Center, get an up-close look at bald eagles in an immersive setting. Finally, stop by the Red Wing Shoe Company flagship store to see the world's largest boot; standing over 20 feet tall, it's a true local icon.
Day 9 - Saturday - Sep 5, 2026
St Paul, United States
St Paul, United States
After breakfast, disembark in this vibrant and dynamic capital city, where you'll enjoy convenient and efficient access to Minneapolis-Saint Paul International Airport for your onward journey. As you travel home, take time to reflect on the incredible experiences you've had and the new friendships you've made along the way. Alternatively, if you're not quite ready for your adventure to end, consider extending your stay to explore the region more fully, discovering even more of its unique attractions and hidden gems.

Other Sail Dates and Itineraries on American Melody

Sail Date Itinerary Name Interior
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Sep 11, 2026(Friday) 8 Night Upper Mississippi River and Land Tour
Departing from St Louis, MO
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$5,635per person$7,795per personView
Sep 11, 2026(Friday) 8 Night Upper Mississippi River and Land Tour
Departing from St Louis, MO
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For Price
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$5,635per person$7,795per personView
Sep 11, 2026(Friday) 8 Night Upper Mississippi River and Land Tour
Departing from St Louis, MO
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$5,635per person$7,795per personView
Sep 25, 2026(Friday) 8 Night Upper Mississippi River and Land Tour
Departing from St Louis, MO
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Sep 25, 2026(Friday) 8 Night Upper Mississippi River and Land Tour
Departing from St Louis, MO
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