Get FREE Price Alerts

Subscribe to our weekly cruise deals email and enjoy FREE price change alerts and updates for this cruise and others like it.

We promise to protect your privacy and personal data. You can review our privacy policy here.

Modify Your Choices
Vacation Type


Filters
Destination
- South America
Travel Dates
Narrow Date Range
Departure Port
- All Departure Ports
Cruise Length
- All Durations
Cruise Line
- All Cruise Lines
Cruise Ships
- All Cruise Ships

Find South America Cruises in October 2027


Sailings per page
62 Matched Sailings
Departing
Itinerary and Ship
Length
Save to
Favorites
Priced from

Oct 31, 2027

(Sunday)

15 Night Grand Voyage Cruise

MSC Divina
MSC Cruises
Starts: Marseille, France
Ends: Rio de Janeiro, Brazil
Ports of Call:
Marseille, Barcelona, Las Palmas, Salvador de Bahia, Ilheus, Ilha Grande, Rio de Janeiro

15 Nights


Add to Favorites
Compare Favorites
from

$1,289

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 30, 2027

(Saturday)

16 Night Grand Voyage Cruise

MSC Divina
MSC Cruises
Starts: Genoa, Italy
Ends: Rio de Janeiro, Brazil
Ports of Call:
Genoa, Marseille, Barcelona, Las Palmas, Salvador de Bahia, Ilheus, Ilha Grande, Rio de Janeiro

16 Nights


Add to Favorites
Compare Favorites
from

$1,429

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 30, 2027

(Saturday)

17 Night Grand Voyage Cruise

MSC Divina
MSC Cruises
Starts: Genoa, Italy
Ends: Santos (Sao Paulo), Brazil
Ports of Call:
Genoa, Marseille, Barcelona, Las Palmas, Salvador de Bahia, Ilheus, Ilha Grande, Rio de Janeiro...

17 Nights


Add to Favorites
Compare Favorites
from

$1,453

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 29, 2027

(Friday)

17 Night Grand Voyage Cruise

MSC Divina
MSC Cruises
Starts: Civitavecchia (Rome), Italy
Ends: Rio de Janeiro, Brazil
Ports of Call:
Civitavecchia (Rome), Genoa, Marseille, Barcelona, Las Palmas, Salvador de Bahia, Ilheus...

17 Nights


Add to Favorites
Compare Favorites
from

$1,453

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 29, 2027

(Friday)

18 Night Grand Voyage Cruise

MSC Divina
MSC Cruises
Starts: Civitavecchia (Rome), Italy
Ends: Santos (Sao Paulo), Brazil
Ports of Call:
Civitavecchia (Rome), Genoa, Marseille, Barcelona, Las Palmas, Salvador de Bahia, Ilheus...

18 Nights


Add to Favorites
Compare Favorites
from

$1,486

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 28, 2027

(Thursday)

18 Night Grand Voyage Cruise

MSC Divina
MSC Cruises
Starts: Naples, Italy
Ends: Rio de Janeiro, Brazil
Ports of Call:
Naples, Civitavecchia (Rome), Genoa, Marseille, Barcelona, Las Palmas, Salvador de Bahia, Ilheus...

18 Nights


Add to Favorites
Compare Favorites
from

$1,517

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 28, 2027

(Thursday)

19 Night Grand Voyage Cruise

MSC Divina
MSC Cruises
Starts: Naples, Italy
Ends: Santos (Sao Paulo), Brazil
Ports of Call:
Naples, Civitavecchia (Rome), Genoa, Marseille, Barcelona, Las Palmas, Salvador de Bahia, Ilheus...

19 Nights


Add to Favorites
Compare Favorites
from

$1,599

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 31, 2027

(Sunday)

22 Night Grand Voyage Cruise

MSC Musica
MSC Cruises
Starts: Civitavecchia (Rome), Italy
Ends: Rio de Janeiro, Brazil
Ports of Call:
Civitavecchia (Rome), Palermo, Ibiza, Valencia, Marseille, Genoa, Marseille, Valencia, Lisbon...

22 Nights


Add to Favorites
Compare Favorites
from

$1,605

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 31, 2027

(Sunday)

23 Night Grand Voyage Cruise

MSC Musica
MSC Cruises
Starts: Civitavecchia (Rome), Italy
Ends: Santos (Sao Paulo), Brazil
Ports of Call:
Civitavecchia (Rome), Palermo, Ibiza, Valencia, Marseille, Genoa, Marseille, Valencia, Lisbon...

23 Nights


Add to Favorites
Compare Favorites
from

$1,659

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 22, 2027

(Friday)

25 Night Grand Voyage Cruise

MSC Divina
MSC Cruises
Starts: Civitavecchia (Rome), Italy
Ends: Santos (Sao Paulo), Brazil
Ports of Call:
Civitavecchia (Rome), Mykonos, Kusadasi (Ephesus), Marmaris, Naples, Civitavecchia (Rome), Genoa...

25 Nights


Add to Favorites
Compare Favorites
from

$2,200

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 30, 2027

(Saturday)

22 Night South American Passage Cruise

Majestic Princess
Princess Cruises
Starts: Southampton, United Kingdom
Ends: Buenos Aires, Argentina
Ports of Call:
Southampton, Vigo, Lisbon, Madeira, Las Palmas, Santa Cruz de Tenerife, Fortaleza, Rio de Janeiro...

22 Nights


Add to Favorites
Compare Favorites
from

$2,569

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 12, 2027

(Tuesday)

21 Night Inca Coast Discovery Segment Cruise

Nieuw Amsterdam
Holland America Line
Starts: San Diego, California
Ends: San Antonio, Chile
Ports of Call:
San Diego, Cabo San Lucas, Huatulco, Puerto Quetzal, Puerto Caldera, Crossing the Equator, Manta...

21 Nights


Add to Favorites
Compare Favorites
from

$2,909

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 07, 2027

(Thursday)

26 Night Inca Coast Mexico and Latin America Legendary Voyage Cruise

Nieuw Amsterdam
Holland America Line
Starts: Vancouver, Canada
Ends: San Antonio, Chile
Ports of Call:
Vancouver, San Francisco, San Diego, Cabo San Lucas, Huatulco, Puerto Quetzal, Puerto Caldera...

26 Nights


Add to Favorites
Compare Favorites
from

$3,479

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 12, 2027

(Tuesday)

36 Night Inca Coast Discovery Collectors Voyage Cruise

Nieuw Amsterdam
Holland America Line
Starts: San Diego, California
Ends: Buenos Aires, Argentina
Ports of Call:
San Diego, Cabo San Lucas, Huatulco, Puerto Quetzal, Puerto Caldera, Crossing the Equator, Manta...

36 Nights


Add to Favorites
Compare Favorites
from

$4,904

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 07, 2027

(Thursday)

41 Night Inca Coast Discovery Collectors Voyage Cruise

Nieuw Amsterdam
Holland America Line
Starts: Vancouver, Canada
Ends: Buenos Aires, Argentina
Ports of Call:
Vancouver, San Francisco, San Diego, Cabo San Lucas, Huatulco, Puerto Quetzal, Puerto Caldera...

41 Nights


Add to Favorites
Compare Favorites
from

$5,424

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 30, 2027

(Saturday)

37 Night South America Passage Grand Adventure Cruise

Majestic Princess
Princess Cruises
Starts: Southampton, United Kingdom
Ends: San Antonio, Chile
Ports of Call:
Southampton, Vigo, Lisbon, Madeira, Las Palmas, Santa Cruz de Tenerife, Fortaleza, Rio de Janeiro...
Special Promotions

37 Nights


Add to Favorites
Compare Favorites
from

$5,719

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 16, 2027

(Saturday)

36 Night Northern Lights Grand Adventure Cruise

Majestic Princess
Princess Cruises
Starts: Southampton, United Kingdom
Ends: Buenos Aires, Argentina
Ports of Call:
Southampton, Trondheim, Tromso, Honningsvag, Alta, Molde, Alesund, Southampton, Vigo, Lisbon...

36 Nights


Add to Favorites
Compare Favorites
from

$5,798

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 09, 2027

(Saturday)

16 Night Trinidad to Rio South American Expedition Cruise

Seabourn Venture
Seabourn Cruises
Starts: Bridgetown, Barbados
Ends: Rio de Janeiro, Brazil
Ports of Call:
Bridgetown, Port of Spain, Devil's Island, Crossing the Equator, Fortaleza, Natal...

16 Nights


Add to Favorites
Compare Favorites
from

$11,399

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 01, 2027

(Friday)

24 Night Southern Caribbean and South American Expedition Cruise

Seabourn Venture
Seabourn Cruises
Starts: Halifax, Canada
Ends: Rio de Janeiro, Brazil
Ports of Call:
Halifax, Carambola Beach, Little Bay, Rodney Bay, Bridgetown, Port of Spain, Devil's Island...

24 Nights


Add to Favorites
Compare Favorites
from

$16,599

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 29, 2027

(Friday)

9 Night King George Island to Puerto Williams Cruise

Silver Endeavour
Silversea Cruises
Starts: King George Island, Antarctica
Ends: Puerto Williams, Chile
Ports of Call:
King George Island, Cruising Antarctica, Antarctic Peninsula, Cruising the Shetland Islands...
Special Promotions

9 Nights


Add to Favorites
Compare Favorites
from

$18,400

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 16, 2027

(Saturday)

13 Night Puerto Williams to King George Island Cruise

Silver Endeavour
Silversea Cruises
Starts: Puerto Williams, Chile
Ends: King George Island, Antarctica
Ports of Call:
Puerto Williams, New Island, West Point Island, Port Stanley, Cruising Antarctica...
Special Promotions

13 Nights


Add to Favorites
Compare Favorites
from

$24,900

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 25, 2027

(Monday)

10 Night Puerto Williams to Puerto Williams Cruise

Silver Wind
Silversea Cruises
Starts: Puerto Williams, Chile
Ends: Puerto Williams, Chile
Ports of Call:
Puerto Williams, Drake Passage, Cruising Antarctica, Antarctic Peninsula...
Special Promotions

10 Nights


Add to Favorites
Compare Favorites
from

$28,000

per person
(double occupancy)
Includes taxes & fees
Learn More

Oct 25, 2027

(Monday)

11 Night Voyage to Antarctica Cruise and Land Tour

National Geographic Resolution
Lindblad Expeditions
Starts: Santiago (Valparaiso), Chile
Ends: Buenos Aires, Argentina
Ports of Call:
Santiago (Valparaiso), Ushuaia, Drake Passage, Cruising Antarctica, Ushuaia, Buenos Aires

11 Nights


Add to Favorites
Compare Favorites

Pricing On
Request

Learn More

Oct 26, 2027

(Tuesday)

10 Night Voyage to Antarctica Cruise

National Geographic Resolution
Lindblad Expeditions
Starts: Ushuaia, Argentina
Ends: Ushuaia, Argentina
Ports of Call:
Ushuaia, Drake Passage, Cruising Antarctica, Ushuaia

10 Nights


Add to Favorites
Compare Favorites

Pricing On
Request

Learn More

Oct 27, 2027

(Wednesday)

12 Night The Emperor Penguins of Weddell Sea Cruise

Le Commandant Charcot
Ponant Cruises
Starts: Ushuaia, Argentina
Ends: Ushuaia, Argentina
Ports of Call:
Ushuaia, Drake Passage, Antarctic Peninsula, Weddell Sea Region, Drake Passage, Ushuaia

12 Nights


Add to Favorites
Compare Favorites

Pricing On
Request

Learn More

Related South America Cruises




Overlay Title