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Find Panama Canal Cruises in April 2026


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28 Matched Sailings
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Apr 12, 2026

(Sunday)

16 Night Panama Canal from Mobile Cruise

Carnival Spirit
Carnival Cruises
Starts: Mobile, Alabama
Ends: Seattle, Washington
Ports of Call:
Mobile, Cartagena, Cruising the Panama Canal, Puntarenas, Cabo San Lucas, Seattle

16 Nights


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$994

per person
(double occupancy)
Includes taxes & fees
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Apr 13, 2026

(Monday)

17 Night Panama Canal Westward Cruise

Celebrity Summit
Celebrity Cruises
Starts: Fort Lauderdale, Florida
Ends: Los Angeles, California
Ports of Call:
Fort Lauderdale, Georgetown , Cartagena, Colon, Cruising the Panama Canal, Puntarenas...

17 Nights


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Retail Price $1,378
Save $160
from

$1,218

per person
(double occupancy)
Includes taxes & fees
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Apr 16, 2026

(Thursday)

16 Night Panama Canal Ocean to Ocean Cruise

Grand Princess
Princess Cruises
Starts: Fort Lauderdale, Florida
Ends: Los Angeles, California
Ports of Call:
Fort Lauderdale, Oranjestad, Cruising the Panama Canal, Fuerte Amador, Puntarenas, Puerto Chiapas...

16 Nights


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$1,249

per person
(double occupancy)
Includes taxes & fees
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Apr 13, 2026

(Monday)

20 Night Panama Canal Ocean to Ocean Cruise

Star Princess
Princess Cruises
Starts: Fort Lauderdale, Florida
Ends: Seattle, Washington
Ports of Call:
Fort Lauderdale, Oranjestad, Cruising the Panama Canal, Fuerte Amador, Mazatlan, Cabo San Lucas...

20 Nights


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$1,424

per person
(double occupancy)
Includes taxes & fees
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Apr 14, 2026

(Tuesday)

20 Night Miami to Seattle Cruise

Queen Elizabeth
Cunard Line
Starts: Miami, Florida
Ends: Seattle, Washington
Ports of Call:
Miami, Cartagena, Colon, Cruising the Panama Canal, Puntarenas, Santa Cruz Huatulco Mexico...
Special Promotions

20 Nights


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$1,589

per person
(double occupancy)
Includes taxes & fees
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Apr 23, 2026

(Thursday)

18 Night Grand Voyage Cruise

MSC Poesia
MSC Cruises
Starts: Miami, Florida
Ends: Seattle, Washington
Ports of Call:
Miami, Cartagena, Colon, Cruising the Panama Canal, Puntarenas, Cabo San Lucas, San Diego...
Special Promotions

18 Nights


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$1,676

per person
(double occupancy)
Includes taxes & fees
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Apr 05, 2026

(Sunday)

14 Night Los Angeles to Miami Cruise

Queen Anne
Cunard Line
Starts: Los Angeles, California
Ends: Miami, Florida
Ports of Call:
Los Angeles, Puerto Quetzal, Cruising the Panama Canal, Willemstad (Curacao), Oranjestad, Miami
Special Promotions

14 Nights


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$1,689

per person
(double occupancy)
Includes taxes & fees
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Apr 11, 2026

(Saturday)

22 Night Panama Canal Cruise

Norwegian Encore
Norwegian Cruise Line
Starts: Miami, Florida
Ends: Seattle, Washington
Ports of Call:
Miami, Cartagena, Cruising the Panama Canal, Panama City, Puerto Caldera, Puerto Quetzal, Acapulco...

22 Nights


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$1,849

per person
(double occupancy)
Includes taxes & fees
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Apr 11, 2026

(Saturday)

18 Night Panama Canal Cruise

Norwegian Encore
Norwegian Cruise Line
Starts: Miami, Florida
Ends: San Francisco, California
Ports of Call:
Miami, Cartagena, Cruising the Panama Canal, Panama City, Puerto Caldera, Puerto Quetzal, Acapulco...

18 Nights


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$1,849

per person
(double occupancy)
Includes taxes & fees
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Apr 25, 2026

(Saturday)

18 Night Panama Canal Cruise

Norwegian Joy
Norwegian Cruise Line
Starts: Miami, Florida
Ends: Seattle, Washington
Ports of Call:
Miami, Cartagena, Colon, Cruising the Panama Canal, Puerto Caldera, Puerto Quetzal, Puerto Vallarta...

18 Nights


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$1,939

per person
(double occupancy)
Includes taxes & fees
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Apr 25, 2026

(Saturday)

15 Night Panama Canal Cruise

Norwegian Joy
Norwegian Cruise Line
Starts: Miami, Florida
Ends: Los Angeles, California
Ports of Call:
Miami, Cartagena, Colon, Cruising the Panama Canal, Puerto Caldera, Puerto Quetzal, Puerto Vallarta...

15 Nights


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$1,959

per person
(double occupancy)
Includes taxes & fees
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Apr 10, 2026

(Friday)

17 Night Panama Canal Cruise

Koningsdam
Holland America Line
Starts: Fort Lauderdale, Florida
Ends: San Diego, California
Ports of Call:
Fort Lauderdale, Cartagena, Cruising the Panama Canal, Fuerte Amador, Puerto Caldera, Acajutla...

17 Nights


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$2,199

per person
(double occupancy)
Includes taxes & fees
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Apr 05, 2026

(Sunday)

27 Night Panama Canal and Caribbean Adventurer Cruise

Grand Princess
Princess Cruises
Starts: San Juan, Puerto Rico
Ends: Los Angeles, California
Ports of Call:
San Juan, St Thomas, Basseterre, Oranjestad, Curacao, Bonaire, Amber Cove, Grand Turk...

27 Nights


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$2,208

per person
(double occupancy)
Includes taxes & fees
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Apr 05, 2026

(Sunday)

15 Night Panama Canal Cruise

Eurodam
Holland America Line
Starts: Fort Lauderdale, Florida
Ends: San Diego, California
Ports of Call:
Fort Lauderdale, Cartagena, Cruising the Panama Canal, Puerto Caldera, Acajutla, Puerto Quetzal...

15 Nights


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$2,214

per person
(double occupancy)
Includes taxes & fees
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Apr 11, 2026

(Saturday)

16 Night Panama Canal from Tampa Cruise

Carnival Miracle
Carnival Cruises
Starts: Tampa, Florida
Ends: Seattle, Washington
Ports of Call:
Tampa, Georgetown , Cartagena, Cruising the Panama Canal, Puntarenas, Cabo San Lucas, Seattle

16 Nights


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$2,219

per person
(double occupancy)
Includes taxes & fees
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Apr 14, 2026

(Tuesday)

30 Night Miami to Seattle Cruise

Queen Elizabeth
Cunard Line
Starts: Miami, Florida
Ends: Seattle, Washington
Ports of Call:
Miami, Cartagena, Colon, Cruising the Panama Canal, Puntarenas, Santa Cruz Huatulco Mexico...
Special Promotions

30 Nights


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$2,391

per person
(double occupancy)
Includes taxes & fees
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Apr 05, 2026

(Sunday)

19 Night Panama Canal Cruise

Eurodam
Holland America Line
Starts: Fort Lauderdale, Florida
Ends: Vancouver, Canada
Ports of Call:
Fort Lauderdale, Cartagena, Cruising the Panama Canal, Puerto Caldera, Acajutla, Puerto Quetzal...

19 Nights


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$2,429

per person
(double occupancy)
Includes taxes & fees
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Apr 10, 2026

(Friday)

22 Night Panama Canal Cruise

Koningsdam
Holland America Line
Starts: Fort Lauderdale, Florida
Ends: Vancouver, Canada
Ports of Call:
Fort Lauderdale, Cartagena, Cruising the Panama Canal, Fuerte Amador, Puerto Caldera, Acajutla...

22 Nights


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$2,499

per person
(double occupancy)
Includes taxes & fees
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Apr 05, 2026

(Sunday)

20 Night Panama Canal with History Channel Cruise

Eurodam
Holland America Line
Starts: Fort Lauderdale, Florida
Ends: Seattle, Washington
Ports of Call:
Fort Lauderdale, Cartagena, Cruising the Panama Canal, Puerto Caldera, Acajutla, Puerto Quetzal...

20 Nights


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$2,559

per person
(double occupancy)
Includes taxes & fees
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Apr 05, 2026

(Sunday)

14 Night Panama Canal Westbound Cruise

Disney Magic
Disney Cruises
Starts: Galveston, Texas
Ends: San Diego, California
Ports of Call:
Galveston, Cozumel, Cartagena, Cruising the Panama Canal, Puerto Vallarta, Cabo San Lucas, San Diego
Special Promotions

14 Nights


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$2,903

per person
(double occupancy)
Includes taxes & fees
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Apr 02, 2026

(Thursday)

32 Night Miami to Seattle Cruise

Queen Elizabeth
Cunard Line
Starts: Miami, Florida
Ends: Seattle, Washington
Ports of Call:
Miami, San Juan, St John's, Castries, Bridgetown, Philipsburg (St. Maarten), Road Town, Miami...

32 Nights


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$2,999

per person
(double occupancy)
Includes taxes & fees
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Apr 14, 2026

(Tuesday)

10 Night Vivid Western Caribbean Cruise

Insignia
Oceania Cruises
Starts: Miami, Florida
Ends: Panama City, Panama
Ports of Call:
Miami, Cozumel, Costa Maya, Belize City, Roatan, Puerto Limon, Colon, Cruising the Panama Canal...

10 Nights


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$3,149

per person
(double occupancy)
Includes taxes & fees
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Apr 02, 2026

(Thursday)

42 Night Miami to Seattle Cruise

Queen Elizabeth
Cunard Line
Starts: Miami, Florida
Ends: Seattle, Washington
Ports of Call:
Miami, San Juan, St John's, Castries, Bridgetown, Philipsburg (St. Maarten), Road Town, Miami...

42 Nights


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$3,899

per person
(double occupancy)
Includes taxes & fees
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Apr 06, 2026

(Monday)

14 Night Star Collector Rainforest Refuges of Panama and Costa Rica via the Panama Canal Cruise

Star Seeker
Windstar Cruises
Starts: San Juan, Puerto Rico
Ends: Puerto Caldera, Costa Rica
Ports of Call:
San Juan, Catalina Island, Santo Domingo, Cartagena, San Blas Islands, Colon...

14 Nights


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$7,980

per person
(double occupancy)
Includes taxes & fees
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Apr 13, 2026

(Monday)

11 Night Panama Canal and the Alluring Islands of the Caribbean Cruise

Scenic Eclipse II
Scenic Cruises
Starts: Panama City, Panama
Ends: Bridgetown, Barbados
Ports of Call:
Panama City, Cruising the Panama Canal, Portobelo, Cayos Limones, Cartagena, Oranjestad...

11 Nights


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$10,680

per person
(double occupancy)
Includes taxes & fees
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